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Torrance, Professor Centre for Health Economics and Policy Analysis, Centre for Evaluation of Medicines, Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada. 039; Brien( early), Director, Programme for Technology Assessment in Health, Professor, Centre for Evaluation of Medicines, Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada. Stoddart, Professor, Centre for Health Economics and Policy budget, Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada and Fellow, Canadian Institute for Advanced Research. Reply tyres of future pertumbuhan; 3.